According to Sacnilk, the movie made Rs 85 lakhs when it debuted on Thursday, the day before Anant Chaturdashi, and added Rs 90 lakhs to that total on Friday.
Vivek Agnihotri had said of the film, "There was a fight whether we will live or not during the Covid pandemic. There was a sizable group of individuals attempting to sell their own nation.
Ahead of the film’s theatrical release in India, Vivek Agnihotri and Pallavi Joshi had hosted special screenings of The Vaccine War in the US under the India for Humanity Tour.